Genetic sperm defects and consanguinity

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Genetic sperm defects and consanguinity.

BACKGROUND The existence of a genetic component to human infertility has been suggested, although neither the specific abnormalities involved, nor their genetic mechanism of transmission, are currently defined. We have examined, by transmission electron microscopy (TEM), ejaculate from 1600 males with fertility problems. Among the subjects studied, we focused on a group of patients whose family...

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Genetic sperm defects.

Genetic sperm defects are specific sperm defects, which have been shown to have a genetic mode of transmission. Such genetic linkage, either direct or indirect, has been associated with a number of sperm defects in different species, with this number increasing with improved diagnostic capabilities. A number of sperm defects, which have proven or suspected genetic modes of transmission are disc...

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Birth defects and parental consanguinity in Norway.

The study compares frequencies of birth defects between immigrant groups and the rest of the Norwegian population in Norway and estimates the influence of consanguinity and socioeconomic factors on these frequencies. The authors studied all 1.56 million births in Norway from 1967 to 1993. Of these, 7,494 children had two Pakistani parents, 84,688 had one Norwegian and one immigrant parent, and ...

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Consanguinity and genetic disorders. Profile from Jordan.

OBJECTIVE With 20-30% of all marriages occurring between first cousins, increasing attention in Jordan is now given to role of consanguinity in the occurrence of genetic diseases. The objective of this study is to define the specific categories of genetic disorders associated with consanguineous marriages. METHODS Etiological categories and consanguinity rates were studied among 623 families ...

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Consanguinity , Inbreeding , and Genetic Drift in Italy

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2001

ISSN: 1460-2350

DOI: 10.1093/humrep/16.7.1365